G Protein Subunit G 13 Binds to Integrin IIb 3 and Mediates Integrin "Outside-In" Signaling
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چکیده
منابع مشابه
The tetraspanin superfamily member CD151 regulates outside-in integrin IIb 3 signaling and platelet function
The tetraspanin family member CD151 forms complexes with integrins and regulates cell adhesion and migration. While CD151 is highly expressed in megakaryocytes and to a lesser extent in platelets, its physiologic role in platelets is unclear. In this study, we investigate the physical and functional importance of CD151 in murine platelets. Immunoprecipitation/ Western blot studies reveal a cons...
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ژورنال
عنوان ژورنال: Science
سال: 2010
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1174779